Parallel Sessions

Preliminary Topics

  • Structure and functions of cytochrome P450s
  • Structural investigation and modeling of biotransformation enzymes
  • Structure and functions of non-cytochrome P450 enzymes (flavin-containing and heme- CYPs in endogenous metabolism of lipids and steroids
  • containing monooxygenases, NAD(P)H quinone oxidoreductases, SULTs, GSTs and UGTs enzymes)
  • Functions of UGTs, GSTs and SULTs enzymes in detoxification
  • Variability of human drug metabolizing CYPs: genetics, epigenetics and ethnicity
  • Drug metabolizing enzymes in drug development
  • Metabolizing enzymes in drug-induced toxicity
  • Experimental models of drug metabolism and disposition
  • Intestinal metabolizing enzymes in bioavailability and disposition
  • Drug transporters and their impact on drug metabolism and disposition
  • AHR and cytochrome P450 CYP1 family
  • CYP1 enzymes in metabolism of endogenous compounds and toxicants
  • Drug, natural compounds, and nutrients metabolism and metabolic interactions
  • Nuclear Xenobiotic Receptors: PXR and CAR in metabolism and diseases
  • Importance of ncRNAs in metabolism regulation
  • Role of liver metabolism in liver disease
  • Crossroads of xenobiotic and endobiotic metabolism
  • Omics and genome-wide tools in the study of drug metabolism
  • Drug metabolism and liver signaling